In 2008, Berkley signed on to star in a multi-episode arc of CSI: Miami, in which she plays Horatio Caine's (David Caruso) ex-lover, Julia Winston, who is also the mother of his recently discovered son. The episodes which Berkley appeared in were very highly rated and all of them featured in the top 10 Nielsen ratings chart. She has since appeared in the show's season six finale and has confirmed that she will be returning for season seven in the fall. She is the host of Bravo's reality series, Step It Up and Dance, a competition featuring the exploits of ten wannabe dancers who compete against each other to win a cash prize of $100,000 as well as the opportunity to work with and perform for some of the country's top choreographers.

The show premiered in April 2008 on Bravo and was very successful, making history for the Bravo network. The show came out as the network's strongest ever in its time slot with 826,000 viewers, among whom 574,000 were aged 18 to 49. The second episode was also very successful in the ratings, with an average of 633,000 viewers for its regular time slot of 9/10c. The show continued to perform well throughout its run, averaging 756,000 viewers each week - of whom 522,000 were aged 18 to 49 - and helped contribute to Bravo's highest-rated April ever.

During the press tour for Step It Up and Dance, Berkley appeared on various shows including various morning news programs, ABC's Jimmy Kimmel Live!, Fuse TV's The Sauce, E!'s Chelsea Lately, CNBC's The Big Idea with Donny Deutsch, and ABC's The View. While on The View, she spoke of her admiration for co-host Whoopi Goldberg, calling her "an extraordinary being". Her appearance on the show was unique in that she brought the ladies of the show tap shoes and taught them a short dance routine. This soon resulted in Joy Behar being bleeped when she cried "Not too fast, I don't want to trip over my tits."

Berkley starred alongside Thomas Jane in the David Arquette directed short film The Butler's in Love which premiered at Mann's Chinese Theater in Los Angeles in June 2008. She has been cast (along with original star Daveigh Chase and Step Up 2 the Streets star Briana Evigan) in the sequel to cult hit Donnie Darko, S. Darko, which is scheduled for release in 2009 and is currently being filmed in Utah. She will play Trudy, a former drug addict turned born again Christian who becomes infatuated with her pastor.

In July 2008, it was confirmed that Berkley will star in a multi-episode arc of the Showtime series The L Word, during its sixth and final season in 2009. She will play the straight girl that got away from Jennifer Beals' character Bette Porter in college. Berkley and Beals are best friends in real life, having previously worked on the 2002 independent film Roger Dodger. It was also confirmed that Berkley, in conjunction with MTV, is developing a reality series which focuses on her Ask-Elizabeth self-help program - and has the same name as its working title, Ask-Elizabeth - for teen girls. The show will follow the actress as she travels around the country and meets with girls of all ages to discuss various topics that are important to them. The show is expected to air in late 2008.

• S. Darko (2009) (post-production) .... Trudy
• Women in Trouble (2009) (completed) .... Tracy
  
• "The L Word" .... Kelly / ... (5 episodes, 2009)
       - Lactose Intolerant (2009) TV episode .... Kelly
       - Litmus Test (2009) TV episode .... Kelly
       - Leaving Los Angeles (2009) TV episode .... Kelly
       - LMFAO (2009) TV episode .... Kelly
       - Least Likely (2009) TV episode .... Kelly Wentworth
• "CSI: Miami" .... Julia Winston (6 episodes, 2008)
       - Bombshell (2008) TV episode .... Julia Winston
       - Resurrection (2008) TV episode .... Julia Winston
       - Going Ballistic (2008) TV episode .... Julia Winston
       - All In (2008) TV episode .... Julia Winston
       - Ambush (2008) TV episode .... Julia Winston
        (1 more)
• The Butler's in Love (2008) .... The Bride
• Black Widow (2008) (TV) .... Olivia
  ... aka Dark Beauty (USA: recut version)
• Meet Market (2008) .... Linda
• "Law & Order: Criminal Intent" .... Danielle Quinn (1 episode, 2006)
  ... aka Law & Order: CI (USA: promotional abbreviation)
       - Dollhouse (2006) TV episode .... Danielle Quinn
• "Threshold" .... Christine Polchek (1 episode, 2005)
       - Progeny (2005) TV episode .... Christine Polchek
• "Without a Trace" .... Post-Makeover Lynette Shaw (1 episode, 2004)
  ... aka W.A.T (USA: short title)
       - American Goddess (2004) TV episode .... Post-Makeover Lynette Shaw
• Moving Malcolm (2003) .... Liz Woodward
• Student Seduction (2003) (TV) .... Christie Dawson
• Detonator (2003) .... Jane Dreyer
  ... aka Detonator - Spiel gegen die Zeit (Germany)
• "CSI: Crime Scene Investigation" .... Renée, Foam Dancer (1 episode, 2003)
  ... aka CSI: Las Vegas (South Africa: English title: informal alternative title) (USA: syndication title)
  ... aka C.S.I. (USA: short title)
  ... aka CSI: Weekends (USA: promotional title)
  ... aka Experts, Les (Canada: French title)
       - Lady Heather's Box (2003) TV episode .... Renée, Foam Dancer
• Control Factor (2003) (TV) .... Karen Bishop
  ... aka Cortex contrôle (Canada: French title)
• "The Twilight Zone" .... Marisa Sanborn (1 episode, 2002)
       - Sanctuary (2002) TV episode .... Marisa Sanborn
• Roger Dodger (2002) .... Andrea
• "Titus" .... Shannon (3 episodes, 2001-2002)
       - Same Courtesy (2002) TV episode .... Shannon
       - Tommy's Crush (2002) TV episode .... Shannon
       - Shannon's Song (2001) TV episode .... Shannon