When Daisy was three years old, the Fuentes family moved to Madrid, Spain, and finally emigrated to Harrison, New Jersey four years later. While studying communications and journalism at Bergen Community College, Daisy was selected as "weather girl" on WXTV Channel 41, Univision's New York affiliate. It didn't take long for the journalism student to move up the ranks, to become news anchor and reporter for the evening news. The Latino television audience took a liking to the talented and beautiful 19-year-old reporter, and soon did a huge network: MTV. In 1988, Daisy moved on to work as news anchor at WNJU Channel 47, Telemundo's New York affiliate.

That same year, she had the confidence to send a demo tape and letter to MTV. She soon retired her news reports for music reports, as host of MTV Internacional, which later became MTV Latino. While hosting and VJ-ing on MTV, Daisy began to develop her acting credits with a role on the ABC soap opera, Loving. She followed her stint on the soap with appearances on shows such as Dream On, The Larry Sanders Show and Cybill. From 1994 until 1995, Daisy became host of her own talk show on CNBC named Daisy, as part of the network's Talk All-Stars. One of her other claims to fame was as host of ABC's America's Funniest Home Videos, for two seasons. She also hosted The Alma Awards in 1997 and 1998; Dick Clark's New Year's Rockin' Eve '98; The 1998 World Music Awards; the 1999 Billboard Latin Awards; as well as Miss Teen USA, Miss USA, and Miss Universe pageants. Daisy is a worldwide Revlon spokesmodel as well as a model for American Express, Pantene, M&M's, and Miller Lite. She can also be seen in 1996 and 1997 Landmark calendars, and keeping fit in her own exercise video. Daisy has graced a wide range of magazines, such as Spanish Cosmopolitan and Harper's Bazaar, as well as Fitness, Latina and Shape.

Hugh Hefner reportedly invited Fuentes numerous times in the early 90's to pose nude in Playboy magazine, but she has insisted that she will never do nude modeling. Fuentes played on the World Poker Tour in the Hollywood Home games for the St. Jude Children's Research Hospital charity. She also has designed a clothing line bearing her name, sold exclusively by Kohl's Department Stores. Her manager works for Shelter Entertainment.

• Lolo's Cafe (2006) (TV) (voice) .... Eve
• "Half & Half" .... Nina (1 episode, 2004)
       - The Big Typecast Episode (2004) TV episode .... Nina
• "The Brothers Garcia" .... Dr. Ramirez (1 episode, 2002)
       - Don't Judge a Book by Its Cover (2002) TV episode .... Dr. Ramirez
• "Queen of Swords" .... Isabel Selvera (2 episodes, 2000-2001)
  ... aka Reina de espadas (Spain)
  ... aka Tessa, à la pointe de l'épée (France)
       - End of Days (2001) TV episode .... Isabel Selvera
       - Running Wild (2000) TV episode .... Isabel Selvera
• "Baywatch" .... Maya Morgan (1 episode, 2000)
  ... aka Baywatch Hawaii (USA: new title)
       - Stone Cold (2000) TV episode .... Maya Morgan
• Shutterspeed (2000) (TV) .... Kenzie Pearson
• "Style World" (2000) TV series .... Host
• "I Spike" (2000) TV series