During the 1990s, Judd dated baseball player Brady Anderson, singers Lyle Lovett and Michael Bolton, and actors Matthew McConaughey and Robert De Niro. In December 1999, she became engaged to Scottish auto racer Dario Franchitti, who was at the time driving in Champ Car World Series (he has since raced in IndyCars and NASCAR). The two were married at Skibo Castle, near Dornoch, Scotland, on December 12, 2001. She and her husband divide their time between a home in Scotland and their farm outside Franklin, Tennessee. Judd can be recognized in Gasoline Alley wearing a white hat, and was present at the 2007 Indianapolis 500 when her husband won.

When in Manhattan, Judd attends services at a charismatic missionary Baptist church. She also regularly attends University of Kentucky basketball games, frequently sitting next to Donna Smith (wife of former Kentucky Coach Tubby Smith), or in the student section. Last year, Judd was a guest columnist for a local Kentucky newspaper, writing about the NCAA championships. She is frequently sought out for celebrity camera shots during televised games. Judd posed for a poster wearing only a hockey jersey for fundraising purposes for their alma mater's hockey team. She is also an avid practitioner of yoga, cooking and gardening. In February 2006, Judd entered a program at Shades of Hope Treatment Center in Buffalo Gap, Texas and stayed for 47 days. She was there because of personal issues, including depression and isolation.

Judd is active in humanitarian and political causes. She was appointed Global Ambassador for YouthAIDS, an education and prevention program of the international NGO Population Services International (PSI), promoting AIDS prevention and treatment, and speaks and demonstrates at pro-choice events. On October 29, 2006, Judd appeared at a "Women for Ford" event for Democratic Tennessee Senate candidate Harold Ford, Jr. A long-running feud between Judd and Indy race car driver Milka Duno took place throughout the 2007 Indy Racing League season. After the final race of the 2007 season, the actress stated to the assembled news media that, "I know this is not very sportsmanlike, but they've got to get the 23 car (Duno) off the track. It's very dangerous. I'm tired of holding my tongue. She shouldn't be out there. When a car is 10 miles (an hour) off the pace, it's not appropriate to be racing. People's lives are at stake."

• Tooth Fairy (2009) (post-production)
• Crossing Over (2009) (completed) .... Denise Frankel
  
• Helen (2008/I) .... Helen
• Bug (2006) .... Agnes White
• Come Early Morning (2006) .... Lucy Fowler
• De-Lovely (2004) .... Linda Porter
• Twisted (2004/I) .... Jessica Shepard
  ... aka Twisted - Der erste Verdacht (Germany)
• Frida (2002) .... Tina Modotti
• Divine Secrets of the Ya-Ya Sisterhood (2002) .... Younger Vivi Abbott Walker
• High Crimes (2002) .... Claire Kubik
• Someone Like You... (2001) .... Jane Goodale
  ... aka Animal Attraction (UK)
• The Ryan Interview (2000) (TV) .... Fredericka Rose
• Where the Heart Is (2000) .... Lexie Coop
  
• Double Jeopardy (1999) .... Libby
  ... aka Doppelmord (Germany)
  ... aka Double condamnation (Canada: French title)
• Eye of the Beholder (1999) .... Joanna Eris
  ... aka Voyeur (Canada: French title)
• Our Friend, Martin (1999) (V) (voice) .... Mrs. Dale
• Simon Birch (1998) .... Rebecca Wenteworth
  ... aka Angels and Armadillos
• Kiss the Girls (1997) .... Dr. Kate McTiernan
• The Locusts (1997) .... Kitty
  ... aka A Secret Sin (UK)